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1

Oxidative Stress Attenuates TLR3 Responsiveness and Impairs Anti-viral Mechanisms in Bronchial Epithelial Cells From COPD and Asthma Patients

Menzel, Mandy, Ramu, Sangeetha, Calvén, Jenny, Olejnicka, Beata, Sverrild, Asger, Porsbjerg, Celeste, Tufvesson, Ellen, Bjermer, Leif, Akbarshahi, Hamid, Uller, Lena

Journal:

Frontiers in Immunology

Year:

2019

File:

PDF, 1.03 MB

2019

2

‘To measure is to know’ (Lord Kelvin)

Ward, Chris, Uller, Lena

Journal:

Year:

2015

Language:

english

File:

PDF, 108 KB

english, 2015

3

House dust mite impairs antiviral response in asthma exacerbation models through its effects on TLR3

Akbarshahi, Hamid, Menzel, Mandy, Ramu, Sangeetha, Mahmutovic Persson, Irma, Bjermer, Leif, Uller, Lena

Journal:

Year:

2018

Language:

english

File:

PDF, 1.05 MB

english, 2018

4

Interferon regulatory factor 3 activation mediates viral stimulus-induced bronchial production of thymic stromal lymphopoietin

Journal:

Journal of Allergy and Clinical Immunology

Year:

2013

Language:

english

File:

PDF, 41 KB

english, 2013

5

Selective inhibition by simvastatin of IRF3 phosphorylation and TSLP production in dsRNA-challenged bronchial epithelial cells from COPD donors

Brandelius, Angelica, Mahmutovic Persson, Irma, Calvén, Jenny, Bjermer, Leif, Persson, Carl GA, Andersson, Morgan, Uller, Lena

Journal:

British Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 2.71 MB

english, 2013

6

Lung Tissue Eosinophils May Be Cleared Through Luminal Entry Rather Than Apoptosis

ULLER, LENA, PERSSON, CARL G. A., KÄLLSTRÖM, LEIF, ERJEFÄLT, JONAS S.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2001

Language:

english

File:

PDF, 495 KB

english, 2001

7

Rhinovirus and dsRNA Induce RIG-I-Like Receptors and Expression of Interferon β and λ1 in Human Bronchial Smooth Muscle Cells

Calvén, Jenny, Yudina, Yuliana, Uller, Lena, Li, Kui

Journal:

Year:

2013

Language:

english

File:

PDF, 3.81 MB

english, 2013

8

Letter to Respiratory Medicine: “Drugs reducing transepithelial leukocyte traffic may worsen lung disease”

Carl Persson, Lena Uller

Journal:

Respiratory Medicine

Year:

2011

Language:

english

File:

PDF, 95 KB

english, 2011

9

Resolution of cell-mediated airways diseases

Carl G Persson, Lena Uller

Journal:

Respiratory Research

Year:

2010

Language:

english

File:

PDF, 1.04 MB

english, 2010

10

Translational value of animal models of asthma: Challenges and promises

Sagar, Seil, Akbarshahi, Hamid, Uller, Lena

Journal:

European Journal of Pharmacology

Year:

2015

Language:

english

File:

PDF, 515 KB

english, 2015

11

Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation

Mahmutovic Persson, Irma, Akbarshahi, Hamid, Menzel, Mandy, Brandelius, Angelica, Uller, Lena

Journal:

Journal of Translational Medicine

Year:

2016

Language:

english

File:

PDF, 7.06 MB

english, 2016

12

Primary lysis of eosinophils as a major mode of activation of eosinophils in human diseased tissues

Persson, Carl, Uller, Lena

Journal:

Nature Reviews Immunology

Year:

2013

Language:

english

File:

PDF, 76 KB

english, 2013

13

Resolution of leucocyte-mediated mucosal diseases. A novel in vivo paradigm for drug development

Carl Persson, Lena Uller

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 857 KB

english, 2012

14

Increased fecal leukocytes may reflect resolution of IBD

Persson, Carl G., Uller, Lena

Journal:

Scandinavian Journal of Gastroenterology

Year:

2011

Language:

english

File:

PDF, 46 KB

english, 2011

15

Azithromycin induces anti-viral effects in cultured bronchial epithelial cells from COPD patients

Menzel, Mandy, Akbarshahi, Hamid, Bjermer, Leif, Uller, Lena

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 889 KB

english, 2016

16

Viral induced overproduction of epithelial TSLP: Role in exacerbations of asthma and COPD?

Uller, Lena, Persson, Carl

Journal:

Journal of Allergy and Clinical Immunology

Year:

2018

Language:

english

File:

PDF, 52 KB

english, 2018

17

Anti-Fas mAb-induced apoptosis and cytolysis of airway tissue eosinophils aggravates rather than resolves established inflammation

Lena Uller, Kristina Rydell-Törmänen, Carl GA Persson, Jonas S Erjefält

Journal:

Respiratory Research

Year:

2005

Language:

english

File:

PDF, 6.15 MB

english, 2005

18

IL-1β mediates lung neutrophilia and IL-33 expression in a mouse model of viral-induced asthma exacerbation

Mahmutovic Persson, Irma, Menzel, Mandy, Ramu, Sangeetha, Cerps, Samuel, Akbarshahi, Hamid, Uller, Lena

Journal:

Respiratory Research

Year:

2018

Language:

english

File:

PDF, 6.49 MB

english, 2018

19

dsRNA-induced expression of thymic stromal lymphopoietin (TSLP) in asthmatic epithelial cells is inhibited by a small airway relaxant

Angelica Brandelius, Yulyana Yudina, Jenny Calvén, Leif Bjermer, Morgan Andersson, Carl Persson, Lena Uller

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 691 KB

english, 2011

20

Resolution of airway disease: removal of inflammatory cells through apoptosis, egression or both?

Lena Uller, Carl G.A. Persson, Jonas S. Erjefält

Journal:

Trends in Pharmacological Sciences

Year:

2006

Language:

english

File:

PDF, 436 KB

english, 2006

21

Research highlights from the 2018 European Respiratory Society International Congress: airway disease

Schleich, Florence, Bikov, Andras, Mathioudakis, Alexander G., McDonnell, Melissa, Andersson, Cecilia, Bonini, Matteo, Uller, Lena, Idzko, Marco, Singh, Dave, Lopez-Campos, Jose Luis, Bossios, Apostol

Journal:

ERJ Open Research

Year:

2019

File:

PDF, 373 KB

2019

22

Lung Tissue Eosinophils May Be Cleared Through Luminal Entry Rather Than Apoptosis

ULLER, LENA, PERSSON, CARL G. A., KÄLLSTRÖM, LEIF, ERJEFÄLT, JONAS S.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2001

File:

PDF, 495 KB

2001

23

Allergens produce serine proteases-dependent distinct release of metabolite DAMPs in human bronchial epithelial cells

Ramu, Sangeetha, Menzel, Mandy, Bjermer, Leif, Andersson, Cecilia, Akbarshahi, Hamid, Uller, Lena

Journal:

Clinical & Experimental Allergy

Year:

2017

Language:

english

File:

PDF, 1.27 MB

english, 2017

24

Rhinovirus-induced IFNβ expression is NFκB-dependent and regulated by the macrophage microenvironment

Menzel, Mandy, Kosinski, Joakim, Uller, Lena, Akbarshahi, Hamid

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1.38 MB

english, 2019

25

Rhinoviral stimuli, epithelial factors and ATP signalling contribute to bronchial smooth muscle production of IL-33

Calvén, Jenny, Akbarshahi, Hamid, Menzel, Mandy, Ayata, Cemil Korcan, Idzko, Marco, Bjermer, Leif, Uller, Lena

Journal:

Journal of Translational Medicine

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

26

Research highlights from the 2018 European Respiratory Society International Congress: airway disease

Schleich, Florence, Bikov, Andras, Mathioudakis, Alexander G., McDonnell, Melissa, Andersson, Cecilia, Bonini, Matteo, Uller, Lena, Idzko, Marco, Singh, Dave, Lopez-Campos, Jose Luis, Bossios, Apostol

Journal:

ERJ Open Research

Year:

2019

Language:

english

File:

PDF, 373 KB

english, 2019

27

ERS International Congress, Madrid, 2019: highlights from the Airway Diseases, Asthma and COPD Assembly

Lahousse, Lies, Bahmer, Thomas, Cuevas-OcaÃ±a, Sara, Flajolet, Pauline, Mathioudakis, Alexander G., McDonnell, Melissa, Uller, Lena, Schleich, Florence, Dortas Junior, Sergio, Idzko, Marco, Singh, Dav

Journal:

ERJ Open Research

Year:

2020

File:

PDF, 562 KB

2020

28

Unbalanced research

Carl G.A Persson, Jonas S Erjefält, Lena Uller, Morgan Andersson, Lennart Greiff

Journal:

Trends in Pharmacological Sciences

Year:

2001

Language:

english

File:

PDF, 219 KB

english, 2001

29

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] C36. LUNG EPITHELIUM, SUBMUCOSAL GLANDS AND SMOOTH MUSCLE - Activation Of Double-Stranded RNA-Sensing Receptors Triggers Type I And Type III Interferon Production By Human Airway Smooth Muscle Cells

Calven, Jenny, Bjermer, Leif, Uller, Lena

Year:

2012

Language:

english

File:

PDF, 20 KB

english, 2012

30

Remodeling of extra-bronchial lung vasculature following allergic airway inflammation

Kristina Rydell-Törmänen, Lena Uller, Jonas S Erjefält

Journal:

Respiratory Research

Year:

2008

Language:

english

File:

PDF, 310 KB

english, 2008

31

Epithelial perviousness in allergic airways disease

Persson, Carl, Uller, Lena

Journal:

Journal of Allergy and Clinical Immunology

Year:

2017

Language:

english

File:

PDF, 51 KB

english, 2017

32

Reduced granulocyte counts in sputum may reflect aggravated disease

Persson, Carl, Uller, Lena

Journal:

Journal of Allergy and Clinical Immunology

Year:

2015

Language:

english

File:

PDF, 43 KB

english, 2015

33

Allergen Exposure of Mouse Airways Evokes Remodeling of both Bronchi and Large Pulmonary Vessels

Törmänen, Kristina Rydell, Uller, Lena, Persson, Carl G. A., Erjefält, Jonas S.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2005

Language:

english

File:

PDF, 277 KB

english, 2005

34

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] D21. MICROBIAL CONTRIBUTIONS TO ASTHMA PATHOGENESIS - DsRNA-Induced TSLP Expression And Neutrophilia In Mouse Asthma Exacerbation Model

Mahmutovic Persson, Irma, Brandelius, Angelica, Uller, Lena

Year:

2012

Language:

english

File:

PDF, 20 KB

english, 2012

35

Neutrophil cannibalism – a back up when the macrophage clearance system is insufficient

Kristina Rydell-Törmänen, Lena Uller, Jonas S Erjefält

Journal:

Respiratory Research

Year:

2006

Language:

english

File:

PDF, 1.14 MB

english, 2006

36

Viral Stimuli Trigger Exaggerated Thymic Stromal Lymphopoietin Expression by Chronic Obstructive Pulmonary Disease Epithelium: Role of Endosomal TLR3 and Cytosolic RIG-I-Like Helicases

Calvén, Jenny, Yudina, Yulyana, Hallgren, Oskar, Westergren-Thorsson, Gunilla, Davies, Donna E., Brandelius, Angelica, Uller, Lena

Journal:

Journal of Innate Immunity

Year:

2012

Language:

english

File:

PDF, 2.03 MB

english, 2012

37

Allergic Airway Inflammation Initiates Long-Term Vascular Remodeling of the Pulmonary Circulation

Rydell-T&ouml, rm&auml, nen, Kristina, Uller, Lena, Erjef&auml, lt, Jonas S.

Journal:

International Archives of Allergy and Immunology

Year:

2009

Language:

english

File:

PDF, 431 KB

english, 2009

38

Interferon-β deficiency at asthma exacerbation promotes MLKL mediated necroptosis

Cerps, Samuel C., Menzel, Mandy, Mahmutovic Persson, Irma, Bjermer, Leif, Akbarshahi, Hamid, Uller, Lena

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 4.98 MB

english, 2018

39

Human host defense peptide LL-37 facilitates double-stranded RNA pro-inflammatory signaling through up-regulation of TLR3 expression in vascular smooth muscle cells

Dahl, Sara, Cerps, Samuel, Rippe, Catarina, SwÃ¤rd, Karl, Uller, Lena, Svensson, Daniel, Nilsson, Bengt-Olof

Journal:

Inflammation Research

Year:

2020

File:

PDF, 4.04 MB

2020

40

Novel Selective Orally Active CRTH2 Antagonists for Allergic Inflammation Developed from in Silico Derived Hits

Ulven, Trond, Receveur, Jean-Marie, Grimstrup, Marie, Rist, Øystein, Frimurer, Thomas M., Gerlach, Lars-Ole, Mathiesen, Jesper Mosolff, Kostenis, Evi, Uller, Lena, Högberg, Thomas

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 90 KB

english, 2006

41

Theirs But to Die and Do: Primary Lysis of Eosinophils and Free Eosinophil Granules in Asthma

Persson, Carl, Uller, Lena

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2014

Language:

english

File:

PDF, 733 KB

english, 2014

42

Early phase resolution of mucosal eosinophilic inflammation in allergic rhinitis

Lena Uller, Cecilia Ahlström Emanuelsson, Morgan Andersson, Jonas S Erjefält, Lennart Greiff, Carl G Persson

Journal:

Respiratory Research

Year:

2010

Language:

english

File:

PDF, 1.23 MB

english, 2010

43

Capacity of capsazepinoids to relax human small airways and inhibit TLR3-induced TSLP and IFNβ production in diseased bronchial epithelial cells

Irma Mahmutovic-Persson, Martin Johansson, Angelica Brandelius, Jenny Calvén, Leif Bjermer, Yuliana Yudina, Lena Uller

Journal:

International Immunopharmacology

Year:

2012

Language:

english

File:

PDF, 1.81 MB

english, 2012

44

Occurrence of Apoptosis, Secondary Necrosis, and Cytolysis in Eosinophilic Nasal Polyps

Uller, Lena, Andersson, Morgan, Greiff, Lennart, Persson, Carl G. A., Erjefält, Jonas S.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2004

Language:

english

File:

PDF, 354 KB

english, 2004

45

Antagonism of the prostaglandin D2receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation

Lena Uller, Jesper Mosolff Mathiesen, Lisa Alenmyr, Magnus Korsgren, Trond Ulven, Thomas Högberg, Gunnar Andersson, Carl GA Persson, Evi Kostenis

Journal:

Respiratory Research

Year:

2007

Language:

english

File:

PDF, 1.24 MB

english, 2007

46

TRPV4-Mediated Calcium Influx and Ciliary Activity in Human Native Airway Epithelial Cells

Alenmyr, Lisa, Uller, Lena, Greiff, Lennart, Högestätt, Edward D., Zygmunt, Peter M.

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2014

Language:

english

File:

PDF, 297 KB

english, 2014

47

Topical dsRNA challenges may induce overexpression of airway antiviral cytokines in symptomatic allergic disease. A pilot in vivo study in nasal airways

Brandelius, Angelica, Andersson, Morgan, Uller, Lena

Journal:

Respiratory Medicine

Year:

2014

Language:

english

File:

PDF, 508 KB

english, 2014

48

Simvastatin-induced effects on bronchial epithelial cells from COPD donors

Journal:

European Respiratory Journal

Year:

2013

Language:

english

File:

PDF, 134 KB

english, 2013

49

Up-regulation of epithelial and fibroblast prostaglandin D2 CRTH2-receptors in asthma

Uller, Lena, Ribbene, Anna, Sammut, David, Howarth, Peter, Holgate, Stephen, Davies, Donna

Journal:

World Allergy Organization Journal

Year:

2007

Language:

english

File:

PDF, 149 KB

english, 2007

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